novel technologies like berkeley lights’ (bli) single plasma cell cloning platform, beacon®, promise to drastically simplify and shorten antibody discovery workflows by identifying a much reduced number of highly functional hits within a few hours of sacrificing the animal. this is achieved by placing thousands of individual plasma cells from the immunized animal into nano-wells called pens, and testing multiple properties of the secreted antibodies in a short time frame. in order to compare the functionality of the beacon platform with a hybridoma approach we generated monoclonal antibodies against pdl1, a frequently used cancer target, using our beacon single plasma cell cloning platform as well as hybridoma technology. pd-l1 is a key inhibitor of t cell activation that is often over-expressed in cancer to escape immune surveillance and promote tumor progression. blocking antibodies against pd-l1 or its receptor, pd-1
chempartner.com是上海睿智化学研究有限公司旗下网站,网站成立于1999年5月25日,该网站属于综合其他行业。网站前端技术使用select2,jquery ui,fancybox,jquery migrate,jquery devbridge autocomplete,jquery,datatables,jquery-pjax,jquery mobile,bootstrap,网站后端技术使用wordpress,wordpress,mysql,php,mediaelement.js。网站已经通过工信部备案,备案号为: 沪ICP备10214210号。已开启GZIP压缩,用户主要来自美国、卢森堡,主要流量来自搜索引擎。chempartner.com的域名年龄为25年1个月6天,注册商为Leascend Technology Co.,Ltd.,DNS为vip3.alidns.com,vip4.alidns.com,域名更新时间是2024年05月24日,域名过期时间是2025年05月25日,距离过期还有328天。解析出来的IP有:151.101.194.159[泛播 Fastly]。